Care that looks for the root contributors to chronic symptoms, designed and supervised by a board-certified physician, alongside your existing care.
Board-Certified Internal Medicine (ABIM) · Fellowship-Trained Allergy & Immunology
Years
Led
Care
These statements have not been evaluated by the FDA. Our therapies are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
Physician-led integrative & regenerative medicine in Encinitas — supervised by Dr. Heather Volpp, MD.
We focus on the root contributors to chronic symptoms — inflammation, oxidative burden, and immune dysregulation — with protocols designed and supervised by a board-certified physician. Care that complements your existing treatment, never replaces it.
Board-certified internal medicine
Clinical practice
Supervised by Dr. Heather Volpp, MD
Allergy & Immunology Fellowship · UCLA/VA · CA License A81147 · Physician-Owned & Operated
These statements have not been evaluated by the FDA. Our therapies are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
— Physician-Led Integrative Medicine · Encinitas, CA
Physician-led integrative & regenerative medicine in Encinitas — supervised by Dr. Heather Volpp, MD.
We focus on the root contributors to chronic symptoms — inflammation, oxidative burden, and immune dysregulation — with protocols designed and supervised by a board-certified physician. Care that complements your existing treatment, never replaces it.
★ Board-Certified Internal Medicine · 25+ years | Physician-owned & operated
— Treatments & Therapies
Principle 01
We are a physician-led practice first. Dr. Heather Volpp’s fellowship training at UCLA in Allergy and Immunology shapes how we assess, diagnose, and treat. Every patient receives a genuine clinical evaluation, not a spa consultation.
Meet Dr. Heather VolppPrinciple 02
Chronic inflammation, immune dysregulation, and cellular energy deficit are the root of most modern health conditions. EBOO, HOCATT®, and PEMF therapies address these mechanisms directly, at the cellular level, where lasting change occurs.
Explore EBOOPrinciple 03
Dr. Heather Volpp practices in conjunction with your existing medical team, never in place of it. Her aim is to optimize your body’s natural healing and calm the chronic inflammation that underlies so many conditions, complementing the care you already trust.
Principle 04
Beautiful skin and vibrant health share the same biology. Our aesthetic treatments, Genius® RF, Lutronic® Ultra, neurotoxins, are administered within a clinical framework designed to complement your health protocols.
Aesthetic ServicesSwipe to continue
Medical ozone introduces a brief, controlled oxidative signal. Research suggests this may prompt the body’s own adaptive antioxidant and repair pathways, so the goal is to support your physiology, not override it.
Our education hub walks through the biology, the current evidence, candidacy, and how EBOO and HOCATT® compare, so you understand the mechanism before the outcome.
Mechanism 01
A small, controlled ozone stressor may stimulate the body’s own antioxidant pathways, including Nrf2, glutathione, and SOD.
Mechanism 02
Research suggests ozone may influence cytokine signaling and immune response, of interest in chronic infection and immune dysregulation.
Mechanism 03
With EBOO, blood is circulated through a hollow-fiber filter as part of the treatment circuit; researchers are exploring its role in supporting normal clearance.
Mechanism 04
EBOO blood-circuit therapy and the HOCATT® transdermal sauna, each suited to different needs and conditions.
Medical ozone can be delivered many ways. Dr. Heather Volpp offers two, each selected for its evidence base and fit within a physician-supervised protocol.
Forms of Ozone Therapy
IV · Blood-Circuit
Extracorporeal Blood Ozonation and Oxygenation filters, ozonates, and oxygenates your blood in a sterile, closed circuit, supervised by Dr. Heather Volpp, MD.
Transdermal · Sauna
An all-in-one ozone steam sauna. You sit in a personal chamber, head comfortably outside, while your body absorbs medical-grade ozone, steam, and heat.
Wondering how these compare to ozone IV (10-pass/MAH) or prolozone? See the full comparison →
Select the concern that sounds like you. Each path explains how our physician-led protocols may help.
Root-cause support for lasting fatigue.
Learn moreUncover a hidden inflammatory driver.
Learn moreSupport for persistent, complex infection.
Learn moreAddress immune dysregulation at the source.
Learn moreFind and address the root driver.
Learn moreSupport healing before and after surgery.
Learn moreSkin health, addressed from within.
Learn moreSupport recovery and performance.
Learn more
— Why SynergyO3 Is Different
Many “wellness” clinics offer ozone without a doctor present. At SynergyO3, Dr. Heather Volpp — board-certified in Internal Medicine and fellowship-trained in Allergy & Immunology — designs your protocol, calibrates your dosing, and is clinically responsible for every session.
Every protocol designed & supervised by Dr. Heather Volpp, MD.
We address inflammation, oxidative burden, and immune dysregulation.
We work alongside your existing care team — never a replacement.
Mechanism explained before outcome. Written pricing before any service.
— Patient Stories
★★★★★
“I received EBOO the other day and feel great. I have been working nights for the past 18 months and felt run down. After treatment, I felt rejuvenated and the inflammation in my joints seems to have eased. Dr. Heather Volpp and her staff were professional and made me feel comfortable from my consultation through treatment. I look forward to seeing results as I continue treatment.”
1 week ago · Google
★★★★★
“I have been coming here for EBOO a few weeks now. I have truly enjoyed my experience, the staff and doctor are so welcoming and truly make me feel welcome and at home! Thank you SynergyO3 team!”
10 months ago · Local Guide
★★★★★
“My husband and I have been to many different EBOO clinics across the country and Dr. Heather and her team are the best! We have seen the most health results out of any clinic due to their UV light add on and their knowledgeable, compassionate care. We went from barely functioning to thriving and having energy for the first time in years. We finally have our life back! Their pricing is very competitive too.”
2 months ago · Google
Verified Google reviews. Individual results are not typical and may vary. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.
— Common Questions
Still have questions? Speak with our team directly — we’re happy to talk through your situation before you commit to anything.
Yes. Every treatment at SynergyO3 is designed and supervised by Dr. Heather Volpp, MD. She reviews your full medical history, calibrates dosing, and is clinically responsible for each session — the key safety difference from non-physician “wellness” clinics.
A phone consultation with Dr. Heather Volpp is $150, credited toward your first EBOO treatment. EBOO is $1,100/session (packages available); HOCATT™ is $160/session. Insurance is not accepted, but HSA/FSA superbills are provided, and you receive written pricing before any service.
Call (760) 450-4602 or book a phone consultation online. Dr. Heather Volpp will review your history and tell you honestly whether our protocols are appropriate for your situation — with no obligation.
Ozone therapy is not FDA-approved for specific conditions and is offered as an integrative medical treatment under physician supervision. These statements have not been evaluated by the FDA. Individual results vary.
It depends on your situation. Many patients begin with a short series and reassess; more complex cases may require more over several months. Dr. Heather Volpp evaluates your response after each session and adjusts the protocol.
No. SynergyO3 works alongside your existing care team as a complementary layer — never as a replacement. Dr. Heather Volpp coordinates with your other providers when clinically appropriate.
— Request a Consultation
Leave your details and our team will reach out within one business day to schedule your phone consultation with Dr. Heather Volpp.
Prefer to talk now? Call (760) 450-4602
✓ Reviewed personally by Dr. Heather Volpp, MD
✓ No obligation — a clear, honest assessment
✓ Consultation fee credited toward treatment
— Get Started
Your body is built to seek its own balance — it just needs the right support to get there. At SynergyO3, we focus on the root contributors to chronic symptoms with physician-led, integrative care designed around your biology.
— Inside SynergyO3
A look inside our physician-led practice in Encinitas — the space, the technology, and the team behind your care.
— Visit Us
Mon–Fri · 8:00am–5:00pm PT · Physician-owned & operated